Kazunori Akimoto Selected Research

PKC-3 protein

11/2018	Atypical Protein Kinase C λ/ι Expression Is Associated with Malignancy of Oral Squamous Cell Carcinoma.
9/2014	Colorectal laterally spreading tumors show characteristic expression of cell polarity factors, including atypical protein kinase C λ/ι, E-cadherin, β-catenin and basement membrane component.
7/2013	aPKCλ/ι is a beneficial prognostic marker for pancreatic neoplasms.
2/2013	High expression of KIBRA in low atypical protein kinase C-expressing gastric cancer correlates with lymphatic invasion and poor prognosis.
8/2011	Coexpression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.
9/2009	aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.

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Kazunori Akimoto Research Topics

Disease

22	Neoplasms (Cancer) 07/2022 - 12/2005
10	Breast Neoplasms (Breast Cancer) 07/2022 - 06/2008
2	Stomach Neoplasms (Stomach Cancer) 02/2013 - 01/2010
2	Prostatic Neoplasms (Prostate Cancer) 08/2011 - 09/2009
1	Triple Negative Breast Neoplasms 12/2021
1	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 01/2021
1	Carcinogenesis 01/2020
1	Lewis Lung Carcinoma 02/2019
1	Squamous Cell Carcinoma of Head and Neck 11/2018
1	Lung Neoplasms (Lung Cancer) 11/2014
1	Adenocarcinoma of Lung 11/2014
1	Pancreatic Neoplasms (Pancreatic Cancer) 07/2013
1	Adenocarcinoma 01/2010
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2009
1	Renal Insufficiency (Renal Failure) 01/2009
1	Cysts 04/2006
1	Extramammary Paget Disease (Paget Disease, Extramammary) 12/2005
1	Infections 01/2005
1	Type 2 Diabetes Mellitus (MODY) 01/2005
1	Glucose Intolerance 01/2005
1	Insulin Resistance 09/2003

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 07/2021 - 12/2005
6	PKC-3 proteinIBA 11/2018 - 09/2009
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2009
3	Estrogen ReceptorsIBA 07/2022 - 01/2017
3	Small Interfering RNA (siRNA)IBA 07/2022 - 01/2020
3	Phenobarbital (Luminal)FDA Link 07/2022 - 01/2022
3	3- (1,3- benzothiazol- 2- yl)- 4- (4- methoxyphenyl)but- 3- enoic acidIBA 12/2021 - 11/2018
2	Aldehyde Dehydrogenase 1 FamilyIBA 07/2022 - 12/2021
2	Phosphates (Orthophosphate)IBA 07/2022 - 01/2022
2	SodiumIBA 07/2022 - 01/2022
2	SymportersIBA 07/2022 - 01/2022
2	Trypan Blue FDA Link 12/2021 - 01/2020
2	Protein Kinases (Protein Kinase)IBA 07/2021 - 02/2013
2	Messenger RNA (mRNA)IBA 07/2021 - 01/2017
2	Cadherins (E-Cadherin)IBA 09/2014 - 01/2010
2	Interleukin-6 (Interleukin 6)IBA 08/2011 - 09/2009
2	protein kinase C lambdaIBA 01/2010 - 06/2008
1	Dihydrotachysterol (AT 10)IBA 01/2022
1	Protein Kinase CIBA 12/2021
1	Atrial Natriuretic Factor (ANF)IBA 12/2021
1	EnzymesIBA 07/2021
1	Gold Sodium Thiomalate (Sodium Aurothiomalate)IBA 07/2021
1	ClaudinsIBA 01/2021
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 05/2020
1	DNA (Deoxyribonucleic Acid)IBA 05/2020
1	nutlin 3IBA 05/2020
1	Auranofin (Ridaura)FDA Link 01/2020
1	GSK 1363089IBA 01/2020
1	CaspasesIBA 01/2020
1	Green Fluorescent ProteinsIBA 02/2019
1	CalnexinIBA 11/2014
1	Collagen Type IV (Type IV Collagen)IBA 09/2014
1	CateninsIBA 09/2014
1	Indicators and Reagents (Reagents)IBA 01/2010
1	Hormones (Hormone)IBA 09/2009
1	Growth Factor ReceptorsIBA 12/2005
1	human ERBB2 proteinIBA 12/2005
1	Staphylococcal Protein A (Protein A)IBA 12/2005
1	Trastuzumab (Herceptin)FDA Link 12/2005
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 12/2005
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 12/2005
1	Glucose (Dextrose)FDA LinkGeneric 01/2005
1	Protein Isoforms (Isoforms)IBA 01/2005
1	SterolsIBA 09/2003
1	Triglycerides (Triacylglycerol)IBA 09/2003
1	Insulin (Novolin)FDA Link 09/2003
1	ElementsIBA 09/2003
1	Sterol Regulatory Element Binding Protein 1IBA 09/2003
1	LipidsIBA 09/2003

Therapy/Procedure

5	Therapeutics 01/2022 - 12/2005
1	Radiotherapy 07/2022
1	Drug Therapy (Chemotherapy) 01/2022
1	Precision Medicine 04/2018
1	Lasers (Laser) 11/2014
1	Gastrectomy 01/2010